Now showing items 1-2 of 2

    • Elevated antioxidant defence in the brain of deep-diving pinnipeds 

      Martens, Gerrit A.; Folkow, Lars; Burmester, Thorsten; Geßner, Cornelia (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-16)
      While foraging, marine mammals undertake repetitive diving bouts. When the animal surfaces, reperfusion makes oxygen readily available for the electron transport chain, which leads to increased production of reactive oxygen species and risk of oxidative damage. In blood and several tissues, such as heart, lung, muscle and kidney, marine mammals generally exhibit an elevated antioxidant defence. ...
    • The roles of brain lipids and polar metabolites in the hypoxia tolerance of deep-diving pinnipeds 

      Martens, Gerrit A.; Geßner, Cornelia; Folkow, Lars; Creydt, Marina; Fischer, Markus; Burmester, Thorsten (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-04-14)
      Lipids make up more than half of the human brain's dry weight, yet the composition and function of the brain lipidome is not well characterized. Lipids not only provide the structural basis of cell membranes, but also take part in a wide variety of biochemical processes. In neurodegenerative diseases, lipids can facilitate neuroprotection and serve as diagnostic biomarkers. The study of organisms ...